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It exerts synergistic, multi-targeted effects on key PCD pathways by: inhibiting excessive apoptosis, maintaining autophagic homeostasis, blocking the inflammatory cascade associated with pyroptosis, mitigating iron-dependent lipid peroxidation, reducing neuronal loss, and enhancing bloodbrain barrier integrity

Caffeine can also worsen dehydration and potentially increase nausea in some people

it also helps in generating heat and boosting mood through the release of endorphins