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In mechanistic terms, 5-Amino-1MQ is studied as a means of conserving cellular SAM and NAD that would otherwise be consumed by NNMT activity a pathway of interest in energy-metabolism and adipose-tissue research

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Side effects at each dose level: what the data actually shows Side effects are dose dependent

In cardiomyocytes, it drives mitochondrial dysfunction and contractile failure, whereas in the vasculature it promotes endothelial dysfunction, vascular remodeling, and inflammation