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Description

Adenine model of chronic renal failure in rats to determine whether MCC950, an NLRP3 inflammasome inhibitor, is a renopreventive

NADPH oxidases are specific source of ROS because they produce ROS in a tightly-controlled manner unlike as in other sources where ROS are produced as a secondary metabolite [57]

Jan 2020;87(2):353-361

Scientists use these documented pharmacokinetic characteristics to explore how tissues respond to oxidative stress and mechanical injury at a microscopic level