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That kind of track record is why its become the go-to GLP-1 therapy for weight management

They are grounded in endogenous biology, often supported by convergent evidence across species and experimental modalities, and frequently act at integrative nodes that coordinate multiple physiological processes

The SELECT trial (NEJM 2023) showed semaglutide 2.4 mg reduced major adverse cardiovascular events by approximately 20% versus placebo in non-diabetic adults with obesity and established cardiovascular disease

"With the socioeconomic constraints, the cost variables that are at play, we have huge concerns that a large percentage of our patient base that is reliant on compounded formularies that you can get for $100 to $200 a month and now they are faced with having to pay $1,000, we're concerned about where those patients are going to go," he said