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Retatrutide (LY3437943) agonist hormone receptor 3 (triple-hormone receptor agonist tri-agonist) the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide 1 (GLP-1), and glucagon obesity phase 2, double-blind, randomized, placebo-controlled trial retatrutide obesity recruit BMI 30 or BMI 27-30 at least one weight-related condition 48 retatrutide 12 mg 5%, 10% 15% 100%, 93% 83% obesity nejm.org/doi/full/10.1056/NEJMoa2301972 Attachments retatrutide ( 322 kB ) 2292

Weight reduction itself provides cardiovascular benefits and can improve overall quality of life for many people

Complementary Pathways As mentioned, GLP-1 drugs work on the gut-brain axis to manage hunger and insulin secretion

This duty requires providers to deliver treatment consistent with what a reasonably careful professional would do under similar circumstances