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In rats treated with an inhibitor of glutathione synthesis, NACA has been found to prevent cataract formation and replenish glutathione levels

Research with senescent rhesus monkeys (aged 20-27 years) showed that Epithalon administration decreased basal plasma levels of glucose and insulin while increasing basal nighttime melatonin levelsreversing age-associated endocrine dysfunction patterns

Studies in humans are more limited, but in a cross-sectional study of the microbiome in women with type 2 diabetes, those treated with metformin had a different microbiome compared with those not treated with the drug (see Fig

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