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Metabolic syndrome is characterized by persistent low-grade inflammation, shown by increased C-reactive protein, inflammatory cytokines, and immune cell infiltration in adipose tissue

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Studies have shown that certain bacterial genera such as Bacteroides, Akkermansia, Faecalibacterium, Roseburia, and Bifidobacterium are negatively associated with T2DM, while others like Blautia, Fusobacterium, and Ruminococcus are positively associated with T2DM [156]

GLP-1 medications like Ozempic cause slowed gastric emptying, which often leads to delayed or blunted effects when taking oral psychedelics like psilocybin or MDMA