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This review summarizes that the effect of GLP-1 is not just through its peripheric effects, but also through its central effects on reward processing as assessed by injection of GLP-1 analogs or GLP-1 itself to intra-NTS, NAc, VTA, LH, lPBN, SUM, BNST, LS for palatable food intake, intra-VTA, NAc, and LS for cocaine, intra-NAc for amphetamine, intra-NAc, NTS, dLS for alcohol, and intra-NTS and IPN for cocaine

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