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After GSH donates its electron, it becomes oxidized and leads to the formation of glutathione disulfide (GSSG)

AD pathogenesis involves a number of interrelated pathways, including amyloid plaque development, tau protein hyperphosphorylation, oxidative stress, neuroinflammation, and metabolic failure (Figure 3)

They demonstrated the versatility of GCE technology in exploring PTMs, particularly the diverse Kla effects, and provided a powerful tool for revealing new regulatory mechanisms and interactions