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Suzuki, N., Koussevitzky, S., Mittler, R

Patients with pre-existing significant hyponatremia, hypokalemia, hypomagnesemia, and/or hypercalcemia should have their electrolyte imbalances corrected before hydrochlorothiazide is initiated

For NHS-funded treatment, patients must have a BMI of 35 kg/m (or 32.5 kg/m in certain ethnic groups) with at least one weight-related comorbidity, or a BMI 30 kg/m (27.5 kg/m in certain ethnic groups) with at least one weight-related comorbidity and a referral to a specialist weight management service