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In a retrospective cohort study, patients with T2DM and concomitant osteoporosis or osteopenia who used DPP-4 inhibitors and no antiosteoporotic medications were divided into two groups: those who switched to a GLP-1 receptor agonist and those who continued on a DPP-4 inhibitor [61]

This dual-pathway activation suppresses appetite through multiple brain centers, slows gastric emptying to extend satiety, and improves insulin sensitivity in muscle and liver tissue

The enlargement of the distance between the cemento-enamel junction and the alveolar crest (crista alveolaris) is a clear sign of bone loss around the tooth

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