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Clinical trials have shown effects on glucose tolerance , energy intake , and weight-related markers

L-Carnitine helps increase stamina and performance in an all-inclusive way since it helps to enhance both physical and mental energy

Intermittent or cyclical medication use is being explored as a potential strategy, though robust clinical trial evidence supporting this approach is lacking

269 The benefits of TZDs in MASLD and fibrosis may be the increased adiponectin levels and the adiponectin-mediated effect on insulin sensitivity and hepatic fatty acid metabolism 270 and the downregulated fibrogenic factors and related pathways, inflammatory pathways like JAK/STAT and NF-B signaling pathways