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Quick Answer: Muscle pain is not a recognized common side effect of GLP-1 receptor agonists based on FDA prescribing information and clinical trial data, though some patients report muscle discomfort likely related to rapid weight loss and muscle mass reduction rather than direct drug toxicity

For patients using GLP-1 medications for type 2 diabetes, hemoglobin A1c may increase after discontinuation if no alternative therapy is initiated, with the magnitude varying based on individual factors and baseline therapy

Clinically, BBS presents with a high prevalence of early-onset obesity (70%90%) linked to hyperphagia (9)