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They do not elicit an immune response, and can be isolated from mesenchymal stem cells (MSCs)

Concordance between the Abbott RT-PCR and the Roche-NGS tests was found for 19 out of 25 samples for this cohort (76%)

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In this study, we combined correlative light and electron microscopy (CLEM), 3D electron tomography (ET), cryo-EM, and all-atom molecular dynamics simulations, along with cell biology and genetic approaches, to investigate plant retrograde transport in the model plant Arabidopsis thaliana , with the following major findings: (1) The CLEM, 3D ET, and immunogold transmission electron microscopy (TEM) analyses revealed distinct spherical vesicles (~3050 nm in diameter) labeled by retromer markers and VSR proteins in Arabidopsis root cells, with nascent vesicles budding from MVBs in Arabidopsis root cells