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30,31 In addition, mitochondrial oxidative stress may also trigger the phosphorylation of glycogen synthase kinase-3 (GSK-3), which activates the mixed lineage kinase 3 (MLK3) protein

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423 The atherogenic, proinflammatory and prothrombotic properties of Lp(a) contribute to its role in ASCVD pathogenesis 424 Notably, 7090% of the serum Lp(a) concentration is genetically determined by the expression of the LPA gene 425,426 and is largely unaffected by diet and lifestyle modifications

S0022-3956(11)00289-5 [pii] [DOI] [PubMed] [Google Scholar] Selek S, Savas HA, Gergerlioglu HS, Bulut M, Yilmaz HR