I also observed a worsening of pre-existing POTS symptoms a condition that, in hypermobile Ehlers-Danlos Syndrome, is not incidental but mechanistically downstream: a recognized consequence of defective extracellular matrix that can produce peripheral venous laxity, impaired lower-extremity vasoconstriction, chronic hypovolemia, and the compensatory hyperadrenergic state that characterizes the neuropathic POTS phenotype
Clinical trials have shown that patients using Wegovy injections for weight loss can lose an average of 15-20% of their body weight over time, especially when combined with healthy eating and physical activity
J Inherit Metab Dis 26(23):181188 Wang IC, Sugai JV, Majzoub J, Johnston J, Giannobile WV, Wang HL (2022) Pro-inflammatory profiles in cardiovascular disease patients with peri-implantitis
Patients and their doctors will want to make decisions about medications and specific doses together, she said