retatrutide developer eli lilly shares safety, tolerability data on its next-gen obesity drug ESC 2024: Retatrutide improves lipid

A selective norepinephrine reuptake inhibitor that takes 4 to 6 weeks to reach full effect

High-dose potassium supplements can be dangerous, especially for people with kidney disease or those taking certain medications like ACE inhibitors or potassium-sparing diuretics

Meta-analyses of these and other studies have demonstrated: Reductions in total cholesterol typically in the range of 15% from baseline, varying by agent and population Decreases in LDL cholesterol ranging from 17%, generally more modest than dedicated lipid-lowering therapies Reductions in triglycerides of 515%, with greater effects often seen in those with higher baseline levels Variable effects on HDL cholesterol , with small increases (1-2%) or neutral effects reported The magnitude of lipid improvements appears to correlate with the degree of weight loss achieved, suggesting that metabolic benefits may be partially mediated through adiposity reduction

Simple weight lifting involves learning form and then increasing weight as you get stronger