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Practical usage guidance: Apply to clean, dry, hair-free skin (upper arm, shoulder, hip, or upper back) Wear for the recommended 8 hours and rotate locations daily to minimize skin irritation Use consistently at the same time daily for at least 4-8 weeks to fairly evaluate effects on cravings and appetite Pair patch use with: Balanced meals emphasizing protein (1.6g/kg), fiber (25-35g), and minimally processed foods Hydration, regular movement, and 7-9 hours of quality sleep Mindful eating strategieschecking hunger cues and slowing down meals Track your progress: Keep a simple journal of patch use, appetite levels, mood, and any warning signs

PlexusDx also offers the Precision Peptide Genetic Test ($99 add-on after your first month of treatment), which maps 14 metabolic pathways and analyzes key variants like GLP1R rs6923761 and FTO rs9939609

Ushio-Fukai M, Nakamura Y

Zero animal lactation studies (publicly available)