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Above certain plasma concentrations, arginase activity increases to compensate, further limiting how much arginine stays available for NOS
In this state, there is often low SAM (S-adenosylmethionine) and elevated SAH (S-adenosylhomocysteine), reflecting reduced methyl group availability
If nausea persists beyond a few weeks or becomes severe, consulting a healthcare provider can help determine the best management strategies or whether dosage adjustments are needed
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