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doi: 10.1074/jbc.M110.172189

Ilyas, Z., Perna, S., Al-Thawadi, S., Alalwan, T

284 This is primarily manifested by defects in energy metabolism, increased oxidative stress, calcium ion imbalance, and abnormal mitochondrial dynamics, all potentially leading to neuronal dysfunction and even apoptosis, exacerbating the neurodegenerative changes in AD