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While they are not reviewed or approved by the FDA for safety or effectiveness, they are made in accordance with strict regulatory guidelines

You should seek medical advice before taking beetroot extract if you: Have any chronic medical condition , including cardiovascular disease, kidney disease, liver disease, or diabetes Take any regular prescription medications , particularly antihypertensives, nitrates, or medications for erectile dysfunction Have a history of kidney stones or are at increased risk of nephrolithiasis Experience low blood pressure or symptoms such as dizziness or fainting Are pregnant, planning pregnancy, or breastfeeding , as safety data in these populations is limited Have a known allergy to beetroot or other members of the Amaranthaceae family Are scheduled for surgery

Various structural alterations were made at the N-terminal such as substitution of D-norleucine for L-norleucine, N-acetylation of norleucine, and replacement of norleucine with GABA in order to improve overall stability by reducing susceptibility to aminopeptidases

JMIR Cancer