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Overall, the benefit-risk profile supports broad use of GLP-1-based therapies in MASLD across most patient subgroups, with individualized monitoring plans for high-risk populations
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This selectivity, combined with a short plasma half-life in animal models, has made ipamorelin a widely used pharmacological tool for isolating GH-axis effects in neuroendocrine, bone-metabolism, body-composition, and gastrointestinal-motility research
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