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LTP and LTD: An embarrassment of riches

According to NICE Clinical Knowledge Summaries, once B12 deficiency is adequately treated and symptoms resolve, routine monitoring of serum B12 levels is generally unnecessary, as clinical response is the primary indicator of treatment effectiveness

The majority of expenditure is associated with the treatment of long-term diabetes-related complications, and landmark studies have indicated that the incidence of these complications can be reduced by improving glycemic control, lowering blood pressure and reducing body weight [3,4,5,6]