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Peroxynitrite can initiate DNA damage, leading to the stimulation of a nuclear enzyme, poly (ADP-ribose) synthase (PARS), which causes a decrease in cellular energy levels and leads to cell death

The development of PTP1B inhibitors for the treatment of obesity is in preclinical stages

The overlap is only that both are peptides studied in gastrointestinal contexts, which is why they sometimes appear together in search results but are entirely different research categories

They were housed under controlled laboratory conditions with a 12h/12 h light/dark cycle, at a constant temperature of 25C 1C and relative humidity of 60% 10%