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NACs antioxidant role is partly indirect through glutathione, and partly direct through its own free-radical scavenging and redox effects

References National Center for Biotechnology Information

Cartilage degeneration in KOA is caused by the destruction of the dynamic balance of chondrocytes caused by activation based on other different aspects, in which the matrix degrades enzyme production and exceeds the ability of chondrocytes to secrete matrix components ( Pathogenesis of knee osteoarthritis Among the various structures that make up the knee joint, damage to hyaline articular cartilage is the main cause of osteoarthritis

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