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The EC50 of GLP1 (7-36) is in the expected 2 digits pM range (25-60pM), while its metabolite shows a potency which is 4 logs lower and falls into the low M range

Examination of antioxidant pathway activity, including superoxide dismutase induction, in cell-based models

Severe depletion of GSH in the Arabidopsis mutant rml1 has been reported to result in growth inhibition and it has been speculated that this effect may be caused by severe oxidation of cytosolic E GSH and redox-dependent inhibition of the cell cycle (Vernoux et al., rml1 seedlings (Meyer and Dick, E GSH , both probes, GRX1-roGFP2 and GRX1-roGFP2-iL were expressed in the cytosol of rml1 and used to measure E GSH in root epidermal cells

Gut Microbes 13 , 120 (2021)