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Preclinical safety data does not always predict human safety outcomes, and the absence of adverse effects in controlled animal studies does not guarantee the same in diverse human populations with varying health conditions and concurrent medications

Activated caspase-1 cleaves proIL-1 and proIL-18 into their mature, bioactive forms, which are secreted to promote local inflammation [29]

They advised that physicians and radiologists discuss these potential risks when recommending CT imaging for women of reproductive age

Smooth muscle caldesmon is an extended flexible monomeric protein in solution that can readily undergo reversible intra- and intermolecular sulfhydryl cross-linking