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2016;231(3):R7799
Immune Function and Systemic Inflammation Glutathione depletion is associated with reduced lymphocyte proliferation, impaired NK cell activity, and dysregulated cytokine production
Multiple mechanisms drive pathological ROS accumulation in diabetic cardiomyocytes, such as inhibition of mitochondrial oxidative phosphorylation elevating O 2 production, activation of NOX by angiotensin II (Ang II) and TNF-, and AGEs-RAGE binding-induced NF-B activation that triggers inflammation and further ROS generation
Pittayanon R, Lau JT, Leontiadis GI, Tse F, Yuan Y, Surette M, et al
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