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Researchers calibrated the CORE model with baseline characteristics from LEAD-1 and projected outcomes, including survival rates, cardiovascular, ophthalmic, and renal events incidence, and healthcare expenditures over 10-, 20-, and 30-year intervals (16)(17)

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*In a 64-week medical study of 307 adults living with obesity, or with overweight and at least one weight-related medical problem, along with a reduced-calorie diet and increased physical activity.