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Ghosh (2004) demonstrated that selenium significantly reduced the incidence of clinical prostate cancer

The primary endpoint measured the percentage of subjects achieving clinical remission at week 12, while secondary endpoints included clinical response rates, symptomatic relief, endoscopic remission, mucosal healing at weeks 12 and 52, plus quality of life assessments using IBDQ and SF-36 scores at multiple timepoints including weeks 24 and 64 during extension treatment