It is likely to be the fifth most common cause of death, following an 8% attribution to the mortality rate in the USA, Canada, and the Middle East [105]
Although the risk appears to be extremely low, it serves as a reminder that all medications carry both benefits and risks
Biliary disease was numerically higher, but did not achieve statistical significance in the primary analysis (aHR 1.5, 95% CI: 0.9-2.5)
Betul Hatipoglu, director of the Center for Diabetes, Obesity and Metabolism at Case Western Reserve University and of the Diabetes and Obesity Center at University Hospitals Cleveland Medical Center, says microdosing Ozempic, Zepbound or another GLP-1 drug might mean: Taking a lower dose than what was prescribed or studied in clinical trials Taking a half-dose every few days instead of a full dose once weekly Taking a full dose less often, such as every 10 or 14 days instead of every seven While these approaches are often grouped together online under the umbrella of "microdosing," they're not exactly the same thing
