Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1
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There is a slight chance, of side effects with collagen supplementation, including: Constipation Diarrhea Reduction of appetite Mild headaches Difficulty sleeping Bloating, heavy feeling, or fullness in the stomach Heartburn Rashes Hypercalcemia (abnormally high calcium levels) Irritability, anxiety, and depression Rarely, collagen supplements can slightly increase the risk of developing kidney stones
Suitable for vegans, coeliacs, and diabetics free from animal ingredients, gluten, and added sugar