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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations COX: cytochrome c oxidase CS: citrate synthase CTNS: cystinosin GSH: glutathione GSSG: oxidized glutathione NC: nephropathic cystinosis PG: pyroglutamic acid References Gahl WA, Bashan N, Tietze F, Bernardini I, Schulman JD 1982 Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

Atomic models were built for both maps, showing good fit to their respective cryo-EM maps and revealing high-resolution structural details (Fig

This is called backloading

NAL, a non-selective opioid antagonist [16, 17], is used to reverse opioid overdose effects [18] and precipitates withdrawal in opioid-dependent individuals