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In essence, LL-37 converts normally non-immunogenic self-DNA into a powerful trigger for autoimmune activation

It consists of two functional components: a protein transduction domain that allows it to penetrate cell membranes, and a Dishevelled binding motif that occupies the site where CXXC5 would normally attach

Also Read: GLP-1 drugs move beyond diabetes and weight loss to multi-organ protection (Edited by Sumavarsha)

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