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Role of intervention: [Explain why the product is necessary to facilitate the intervention] Conclusion: In light of the patients diagnosis and research indicating clinical benefit, [product/service] is medically necessary as part of the treatment plan

Nevertheless, the current evidence remains largely inconclusive and does not demonstrate any clear benefit of a gluten-free diet (GFD) in patients without concomitant celiac disease, warranting further investigation [141,144,145,146,147,148,149]

Several factors influence how these numbers translate to individual expectations

Food and Drug Administration (FDA) granted accelerated approval to resmetirom for adults with non-cirrhotic MASH and stage F2F3 fibrosis, thereby establishing the first regulatory foothold in this therapeutic area [15]