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Alison Kraayvanger of the Neighbourhood Pharmacy Association of Canada said pharmacists are able to substitute the generic for the brand product in accordance with existing provincial substitution rules, unless the prescriber has indicated otherwise or there is a clinical reason the patient requires the brand product [Source: globalnews.ca/news/11857122/generic-semaglutide-canada-sales-begin]

Chronic toxicity: Long-term or repeated low-level occupational exposure data for laboratory personnel handling GLP-1 is limited

The medication is available in pre-filled pens containing doses of 0.25 mg, 0.5 mg, 1 mg, or 2 mg

Blood pressure improvements were equally striking, with 41% of participants on 8mg doses discontinuing at least one antihypertensive medication by study completion