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316 These findings provide scientific evidence for developing new OA treatment strategies, confirming the potential of GLP-1 agonists in treating OA

More commonly, Rybelsus is used as combination therapy alongside other glucose-lowering medications, including: Metformin the first-line treatment for type 2 diabetes Sulfonylureas though this combination may increase hypoglycaemia risk Sodium-glucose co-transporter-2 (SGLT2) inhibitors Insulin when additional glycaemic control is required Before prescribing Rybelsus, healthcare professionals will assess several factors, including current HbA1c levels, body mass index (BMI), cardiovascular risk profile, kidney function, and previous medication history

Alcohol Clin Exp Res 23:15961604 Caputo F, Skala K, Mirijello A, Ferrulli A, Walter H, Lesch O, Addolorato G (2014) Sodium oxybate in the treatment of alcohol withdrawal syndrome: a randomized double-blind comparative study versus oxazepam

Combined approach most effective