glutathione function in liver Changes Content in Diseases: An Update Here's Why It's Important to

Riboflavin-responsive trimethylaminuria in a patient with homocystinuria on betaine therapy

While some interventions, such as the use of caspase inhibitors that directly prevent apoptotic cell death [556, 557], are readily classified as neuroprotective, others, including anti-inflammatory agents or metabolic modulators, have more systemic or indirect effects, rendering their categorization less straightforward

Because of the theoretical benefits of maintaining antioxidant defenses to combat various acute and chronic diseases, reducing the consequences of aging and reducing tissue damage from exposure to environmental oxidants, therapeutic approaches to increase systemic and/or tissue-specific glutathione concentrations are of considerable investigational interest

Hacein-Bey-Abina S, Fischer A, Cavazzana-Calvo M