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However, the concentrations of both allopurinol and oxypurinol achieved during in vivo pharmacotherapy seem to be too low for their antioxidant effect (if there is any) to be of therapeutic importance (Halliwell and Gutteridge, 2015)
Acknowledgements This open-access review paper was supported by The project New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM, project ID CZ.02.01.01/00/22_008/0004607, is co-funded by the European Union, and the Erasmus+ Programme of the European Union, Key Action 2: Strategic Partnerships, Project no