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However, some patients may experience persistent fatigue, which warrants further clinical evaluation to exclude other contributing factors such as nutritional deficiencies (particularly iron, vitamin B12, or vitamin D), thyroid dysfunction, or inadequate protein intake

It says freezing destroys the active compound and makes the injection both ineffective and unsafe, and it names ice crystals as one of the signs to look for during inspection

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These disorders are often characterized by cognitive decline, including attention deficits, memory impairment, and reduced executive function, which may persist for months or even years after surgery (Rengel et al., 2023)