increased anxiety on glp 1 GLP-1s linked to lower rates of and depression than an older anti-obesity drug — not higher. #GLP1 #Semaglutide #Tirzepatide #ObesityMedicine #MentalHealth #Anxiety #Depression #Neuropsychiatry #ObesityTreatment #WeightManagement #Naltrexone Ozempic: GLP-1s Linked to 42%

1,2 For this reason, its important to further understand the mechanism of GLP-1 therapies, said Lorenzo Leggio, a neuroendocrinologist at the National Institute on Drug Abuse who mediated the GLP-1 press conference at the 2025 Society for Neuroscience meeting

This is particularly relevant for oral contraceptives, which may have reduced effectiveness during tirzepatide initiation and after each dose increase

130,492,493 NASH is a liver disease primarily caused by fat accumulation, which can progress to liver fibrosis, cirrhosis, or even liver cancer

Reference the retatrutide dosing guide for additional adjustments based on tolerance