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Indeed, it has been suggested that agents capable of achieving an average weight reduction of about 15% in individuals with obesity represent a new generation of anti-obesity medications, as this level of weight loss is sufficient to combat or prevent a broader range of obesity-related complications (238)

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Another important point is the considerable genetic variability within the meningococcal population, which is reflected in marked differences between the various strains, even those belonging to hypervirulent lineages, in their mechanisms of interaction with the host cell and microevolution