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Additionally, they activate the AMPK pathway in liver cells, which promotes fatty acid oxidation and reduces lipid accumulation (lipogenesis), offering potential benefits for non-alcoholic fatty liver disease (NAFLD) (Zheng et al., 2024)

(2025, July 1)

Ongoing research into nutritional and exercise interventions, as well as novel pharmacological agents such as myostatin/activin pathway inhibitors (243) or agents targeting the apelin pathway (244) holds promise for preserving lean mass and improving overall health in patients undergoing treatment with GLP-1 and dual GIP/GLP-1 receptor agonists

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