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Vieira MJ, Gama-Rodrigues JJ, Habr-Gama A, Faintuch J, Waitzberg DL, Pinotti HW
The expression of GCH1 induces the production of potent endogenous RTA, such as BH4/BH2, which block lipid peroxidation and ferroptosis
A double-blind, randomized, placebo-controlled trial demonstrated that perioperative high-dose intravenous injection of Gln (0.5 g/kg/day, P.O for 3 days) raised plasma Gln concentrations and maintained plasma GSH levels in postoperative patients undergoing cardiopulmonary bypass (CPB) [113]
Broadening horizons: the role of ferroptosis in cancer
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