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Temperature was measured daily before and after administration to evaluate the body temperature changes of the mice

Reducing the load to 70A produced the same result, with temperatures still surpassing the safety threshold

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Furthermore, GLP-1 in obese mice reduces hepatic gluconeogenesis by inhibiting phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) [22]