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Semaglutide is part of the GLP-1 receptor agonist class of drugs, which includes other medications like Liraglutide and Exenatide

Brand names you've probably heard include Ozempic, Wegovy, Zepbound, and Mounjaro

Everything else is shared, a 23-membered macrocycle closed by a lactam bridge between the aspartate side-chain carboxyl at position 5 and the lysine side-chain amine at position 10, norleucine at position 4 in place of the oxidation-prone methionine of the native hormone, and D-phenylalanine at position 7 inside the conserved His-Phe-Arg-Trp message core