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Hypothyroidism has been proposed as a contributory mechanism in the pathophysiology of NAFLD, but to date, no human studies showed an association between circulating TH and histological features of NAFLD despite TH are crucial in the regulation of many hepatic metabolic processes and the transcription of several lipogenic genes, whose expression are altered in NAFLD

Jie 2014

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Proc Natl Acad Sci USA 116(25):1245212461 Muir A, Danai LV, Vander Heiden MG (2018) Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies