NNMT and Cancer Elevated NNMT expression has been observed in several forms of cancer, including gastric, pancreatic, renal cell carcinoma, and bladder cancers
Prescribers are advised to: Review eGFR before initiating treatment and consult the relevant SmPC for renal-specific guidance Monitor renal function periodically during therapy, particularly in those with CKD, risk factors, or on nephroactive medicines Counsel patients on adequate hydration, especially during periods of illness or reduced oral intake Patients should always ensure their prescriber is aware of any kidney condition before starting any weight loss medication
"It's hard to find anything that scrutinizes [these medications] because it's drowned out in the positive experiences," McDaniel says
Fernandez-Sanchez L, Lax P, Esquiva G, Martin-Nieto J, Pinilla I, Cuenca N