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Tirzepatide (Zepbound) Clinical trial data cited by multiple sources, including NBC News, showed average weight loss of approximately 21 to 22.5 percent at the highest dose after 72 weeks, compared with about 3 percent for placebo

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However, the company has guided for accelerated generic erosion in Somatuline from mid-2025 onwards as additional generics enter the market in the US and Europe a headwind that will challenge revenue growth through the 20262028 period

That is the mechanistic case for the blend in one paragraph and it is exactly why the two are described as complementary rather than redundant