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Dosage goes up incrementally: 0.25mg Starter dose taken once weekly for the first 4 weeks to help your body adjust and reduce the risk of side effects 0.5mg Second step dose, usually taken for 4 weeks, allowing your body to continue adapting 1mg Mid escalation dose that begins to deliver stronger appetite suppression 1.7mg Higher step up dose used before reaching maintenance, supporting increased effectiveness 2.4mg Typical maintenance dose for long-term weight management and maximum clinical benefit In the first few weeks, many people feel full sooner during meals and are less tempted by large portions or late-night snacks

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The administration of epigenetic drugs leads to unintended effects which modify gene expression throughout different body tissues (222)

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